Wes Brown and Nemanja Vidic will take up the central defensive positions with Patrice Evra, left back and Darren Fletcher on the right back leading the back four for Manchester United against Aston Villa.
Ryan Giggs, Antonio Valencia and Wayne Rooney are also in the starting line up, with Rooney replacing Michael Owen from last week’s Champions League game in Germany, as the lone striker.
Tomasz Kuszczak has again taken up his spot in the goal, following some excellent run in both the Premier League and in Europe in the last couple of weeks.
Among the subs for United are Dimitar Berbatov and youngsters Darron Gibson and Gabriel Obertan.